Satellite Reign

Very deep customizable characters, from weapons to their genetics and base stats. Just as an example, before Watch Dogs: Legions did this "All NPC are/can be a part of your team" thing, they did that 5 years earlier.
The NPCs are also quite believable. For example, when they find a body they, don't instantly know who killed whom and therefore aren't magically running towards you like you left a business card at the body. It gives more depth into your strategies. You could for example take over a Policeman and make him into a decoy at the front door of a private company's security, so they attack him, which afterwards get more Police NPCs to the scene, where they just see how a bunch of private guards attack a colleague and make them attack them too. It's very cool and sometimes by pure chance stuff like this happens on their own.
The enemies are good balanced too, between dumb enough to not be frustrating, but also smart enough to be a threat and make you play carefully. It's almost a incie version of a cyberpunk GTA or in other words, a (currently) better indie version of CP77.
There are still some negatives. The quests aren't very varied and while the areas feel and play great, the overall area designs are quite similar and make it a bit boring after a while. There aren't many uniquely designed areas besides 1 or 2. Also, even tho I took my time with the game, it was only about 16h long. You could probably beat it quite a bit faster, even without speedrunning it. I guess all that comes probably from being a very unknown indie studio with not too much of a budget to spare.
Overall, I would say, if you like the setting and Iso-Realtime-RPGs, with the option to pause (similar to Dragon Age: Origins), it's almost a must play. But even without being an enthusiast, unless you actually hate any or all of those aspects, it's quite a solid game on a sale.

I got this for free off a Humble Bundle a few years back, beat it a while back too, but had a decent time with it. Get it on sale and expect a short 20-25 hour ride. It's got scratches and dings on the surface, but it was memorable enough that I came back just to write this.

Once you figure out what the heck is going on, it's a really fun game. My advice is do not worry about dying. At all. Once you realize cloning isn't important and your dudes are meaningless, it turns into a really fun game. There's just a hump at the beginning where it feels like you are playing "wrong". You can't lose. Just keep grinding.

Needs a sequel

If you're looking for Syndicate Wars, you may be disappointed.
That's not to say this is a bad game. Far from it.
Control 4 agents with different abilities, upgrade their skills, steal and research new weapons, cybernetics and gear, bribe people, assassinate other people, escort one or two others, sneak through vents and upload viruses to ATMs to siphon money from banks. It's a BIT like missions in Syndicate, only open world, so there's no fancy "Mission Accomplished" scene after you rob a bank.
Your goal is to bring down the ruling megacorporation. They have all the cool tech you want, so to begin with you'll need to be sneaky. Once you get your hands on some armour and shields then your agents become a lot more resilient. Especially the Soldier; As well as being able to use heavy weapons, he can draw enemy fire away from the others, and has damage resistance abilities. His big insulated cyber-arms also let him hardwire high voltage equipment, allowing him to disable power sources, make power lines safe to zipline down, and so on. The other agents are useful in their own ways. The Support agent can increase shield and health regen, mark priority targets for damage buffs, and generally keep the team alive. They also have an augmented vision mode that lets you track underground cables, scan NPCs to see whether they'd make good replacement agents, that sort of thing. The Hacker, well, hacks things. They can unlock doors, disable cameras, and "persuade" up to 5 other units to switch sides by overriding their cybernetics. The Infiltrator is your stealth expert, and gets big bonuses to sniper weapons, a hugely powerful melee attack, and a light bending cloak.
The city is huge. There's a lot to keep you busy. It looks gorgeous. The music is very reminiscent of the Syndicate games. The action is more tactical. You can take on forces much bigger as long as you keep an eye on your ability cooldowns, and once you get the hang of what weapons fare best against armour (plasma) and shields (lasers). Each agent can pack a pistol and rifle to begin with, and diversity of weapons is important to match the oncoming threats.
What else? There's a large variety of enemy types, from tiny robodog harassers to riot troops with near-impenetrable shields to ability jamming countermeasure dudes to freaking battle mechs. There's lore to be found, if you want to know more about the city. There are poisonous vents in the Industrial Zone.
It's not Syndicate. It's something very LIKE Syndicate, but still very much its own thing. I have enjoyed my time with it immensely, and let's face it, until EA is torn down and all the IPs it devoured are set free, it's the closest thing you're going to get to a spiritual successor.

Personally, I love this game. for 30 bux its not a bad experience.
To keep this short Satellite Reign simply scratches an itch no other game can. Yes there are cyberpunk games out there but this ones game play is quite unique. Combining RTS with CRPG and a nice rather open feeling cyberpunk world.
It's clunky at times yes but I really hope more games like this come out. I have yet to enjoy a cyberpunk game as much as I have this one and Cyberpunk is a setting I'd love to play but so few games really do it well.
This game and The Ascent are my top two atm.

Modern Syndicate!