In 1999, a man who goes by the alias 47 is initiated into the International Contract Agency, demonstrating exceptional aptitude as an assassin. However, the ICA is unable to verify his background or uncover any information about him. Uncomfortable with having no leverage over 47, the ICA training director, Erich Soders, arranges for 47 to fail his final test despite passing all of the other tests flawlessly.
47's handler and fellow trainee, Diana Burnwood, discovers this plot and helps 47 to pass the test against Soders' order of having him do it alone. Soders reluctantly approves agent status for 47 and assigns Diana as his handler. The events of 47's subsequent career are then shown as a montage of assassinations from the previous games in the series.
In 2019, the shadow client performs an assassination for Viktor Novikov, one of the heads of the international spy ring IAGO, and receives a copy of all of IAGO's gathered intelligence as payment. The shadow client proceeds to use the IAGO files to identify Providence's secret operations.
To cover his tracks, the shadow client anonymously discloses to MI6 an impending IAGO auction of an MI6 NOC list, to take place at a fashion show by Novikov's designer label Sanguine. In Episode 1, "The Showstopper", MI6 hires 47 to prevent the sale by assassinating both IAGO ringleaders, Novikov and Dalia Margolis, at the fashion show in Paris, France.